Search Result "the regulated intramembrane proteolysis mechanism"


Structural and Functional Determinants of γ-Secretase, an Intramembrane Protease Implicated in Alzheimers Disease

Journal: Current Genomics
Volume: 8 Issue: 8 Year: 2007 Page: 531-549
Author(s): Patrick C. Fraering

Similar Mechanisms Regulated by γ-Secretase are Involved in Both Directions of the Bi-Directional Notch-Delta Signaling Pathway as well as Play a Potential Role in Signaling Events Involving Type 1 Transmembrane Proteins

Journal: Current Stem Cell Research & Therapy
Volume: 3 Issue: 4 Year: 2008 Page: 288-302
Author(s): Kohzo Nakayama, Hisashi Nagase, Masahiro Hiratochi, Chang-Sung Koh, Takeshi Ohkawara

Ectodomain Shedding and Regulated Intracellular Proteolysis in the Central Nervous System

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 10 Issue: 4 Year: 2010 Page: 337-359
Author(s): Pavel Montes de Oca-B

Alpha-Secretase Cleavage of the Amyloid Precursor Protein: Proteolysis Regulated by Signaling Pathways and Protein Trafficking

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 165-177
Author(s): Stefan F. Lichtenthaler

An Overview of Notch Signaling in Adult Tissue Renewal and Maintenance

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 227-240
Author(s): Chihiro Sato, Guojun Zhao, Ma. Xenia G. Ilagan

γ-Secretase-Regulated Signaling Typified by Notch Signaling in the Immune System

Journal: Current Stem Cell Research & Therapy
Volume: 8 Issue: 5 Year: 2013 Page: 341-356
Author(s): Hisashi Nagase, Kohzo Nakayama

Expression and Functions of LRP-2 in Central Nervous System: Progress in Understanding its Regulation and the Potential Use for Treatment of Neurodegenerative Diseases

Journal: Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 10 Issue: 4 Year: 2010 Page: 249-254
Author(s): Carlos Spuch, Carmen Navarro

AICD Nuclear Signaling and Its Possible Contribution to Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 200-216
Author(s): Uwe Konietzko

γ-Secretase-Regulated Signaling: Notch, APP, and Alzheimers Disease

Journal: Current Psychopharmacology
Volume: 1 Issue: 2 Year: 2012 Page: 155-166
Author(s): Kohzo Nakayama, Hisashi Nagase, Chang-Sung Koh, Takeshi Ohkawara

γ-Secretase-Regulated Signaling Pathways, such as Notch Signaling, Mediate the Differentiation of Hematopoietic Stem Cells, Development of the Immune System, and Peripheral Immune Responses

Journal: Current Stem Cell Research & Therapy
Volume: 6 Issue: 2 Year: 2011 Page: 131-141
Author(s): Hisashi Nagase, Chang-Sung Koh, Kohzo Nakayama

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